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nLC™ System

Gilson’s versatile nLC™ System accommodates columns from 75 µm to 1 mm in diameter, providing you with a single solution for nano, capillary or micro LC. This system provides an important tool for protein analysis—only the nLC System can deliver gradient elution down to 300 nL/min without a flow splitter. This allows the system to maintain constant flow rates independent of column backpressure.

The system's air gap detectors ensure precise positioning of nanoliter sample volumes in the loop while minimizing sample waste. The system also provides column-switching capability, which allows sample cleanup and preconcentration on the same system.

With Gilson’s nLC System, users can develop multidimensional protocols that include sample preparation and injections from 96-, 384- or 1,536-well plates.

Features & Benefits
  • Splitless flow gradient delivery for nano to micro flows


  • Flexible column switching capability for applications including multidimensional chromatography, sample enrichment and more


  • Column-switching capability allows sample cleanup and preconcentration on the same system


  • Precise injection design saves on costly samples and reagents due to reduced sample injection size and solvent consumption

Applications

  • LC/MS/MS and proteomic applications
  • Protein analysis

845ZPREP™ System



 
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155/156 UV/VIS Detectors User's Guide
250 Nano Injector User's Guide
350 Micro Pump User's Guide
506C User's Guide
 
Sample Loading Capacity
0.1 ng–200 µg
Optimal Column Size 180 µm–2 mm
Flow Rate 0.3–50 µL/min
Maximum Pump Pressure 4,350 psi (300 bar)

 
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