LC/MS Autopurification System
Gilson's NEBULA™ Series LC/MS Autopurification System is designed for selective semipreparative applications. The source of the MSQ provides a
rugged interface to the mass analyzer and can run for extended periods between cleaning.
Features & Benefits
Easy-to-use, UV- or mass-based purification system
Injection and fraction collection on the same bed
Real-time traces both from MS and UV for on-screen comparison
Chromatographic trace is generated from the summed extracted ion chromatogram of up to seven masses
MS interface is ideal for non-volatile buffers, enabling continuous operation for weeks
Ability to add samples on the fly for increased flexibility
Collection by slope, level, time and drop. Collection can be set for peaks and non-peaks
Advanced reporting allows the mass labeling of each peak with optional background-subtracted base peak
VALVEMATE® Valve Actuator provides automatic column switching capability to maximize throughput
Full-scan MS data collection leads to greater confidence in identification of collected fractions
Performs both negative and positive ionization
Sample Loading Capacity
50 mg/mL with 1:1000 splitter
Optimal Column Size
4.6–20 mm
Flow Rate
0.2–30 mL/min
Maximum Injection Pressure
5,000 psi (345 bar)
Maximum Pump Pressure
H1: 8,700 psi (600 bar); H2: 4,350 psi (300 bar)